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Project Discovery: Challenging & Interesting Samples

First post
Author
Cyrano Garjuiji
Praetorian Heavy Industries
The Praetorian Guardsmen
#201 - 2016-09-01 17:06:56 UTC
I probably should have uploaded these here sooner. just found this thread and reminded me of some interrresting screenshots I took.


can anyone tell me what those "things" are?

http://i.imgur.com/8mdaZPv.png

and

http://i.imgur.com/rSEyqWD.png

sorry for not keeping the number tho.
HPA Illuminator
H P A
C C P Alliance
#202 - 2016-09-02 06:51:37 UTC  |  Edited by: HPA Illuminator
Cyrano Garjuiji wrote:
I probably should have uploaded these here sooner. just found this thread and reminded me of some interrresting screenshots I took.


can anyone tell me what those "things" are?

http://i.imgur.com/8mdaZPv.png

and

http://i.imgur.com/rSEyqWD.png

sorry for not keeping the number tho.


What you see there is a cell undergoing cell division (mitosis). The chromosomes (DNA, blue) have duplicated and condensed and lined up next to each other. The microtubules (red) have disassembled to form the mitotic spindle (red), which will attach to sites on the chromosomes and will pull them apart with the help of centrosomes. This will result in two (small) daughter cells that each have a copy of the DNA. After division they don't immediately detach, but are sort of stuck together (via the cytokinetic bridge), before cut off at the cytokinetic bridge cleavage site.

In the first image it seems like there's some green staining overlapping with the red, which would suggest that the protein might help out with the pulling apart of the chromosomes. The second image seems to show an overlap with blue and green, possibly indicating a DNA-binding protein.
Cyrano Garjuiji
Praetorian Heavy Industries
The Praetorian Guardsmen
#203 - 2016-09-02 09:24:38 UTC
HPA Illuminator wrote:
Cyrano Garjuiji wrote:
I probably should have uploaded these here sooner. just found this thread and reminded me of some interrresting screenshots I took.


can anyone tell me what those "things" are?

http://i.imgur.com/8mdaZPv.png

and

http://i.imgur.com/rSEyqWD.png

sorry for not keeping the number tho.


What you see there is a cell undergoing cell division (mitosis). The chromosomes (DNA, blue) have duplicated and condensed and lined up next to each other. The microtubules (red) have disassembled to form the mitotic spindle (red), which will attach to sites on the chromosomes and will pull them apart with the help of centrosomes. This will result in two (small) daughter cells that each have a copy of the DNA. After division they don't immediately detach, but are sort of stuck together (via the cytokinetic bridge), before cut off at the cytokinetic bridge cleavage site.

In the first image it seems like there's some green staining overlapping with the red, which would suggest that the protein might help out with the pulling apart of the chromosomes. The second image seems to show an overlap with blue and green, possibly indicating a DNA-binding protein.

Thank you for the explanation.
Cyrano Garjuiji
Praetorian Heavy Industries
The Praetorian Guardsmen
#204 - 2016-09-09 18:21:28 UTC
Sample 100456307 clearly has 2 bridges answer atleast partially incorrect.

http://i.imgur.com/KxVICk4.png

HPA Illuminator
H P A
C C P Alliance
#205 - 2016-09-22 10:49:57 UTC
Cyrano Garjuiji wrote:
Sample 100456307 clearly has 2 bridges answer atleast partially incorrect.

http://i.imgur.com/KxVICk4.png




Yes, but the cytokinetic bridges are only seen in the red channel, not the green, and should thus not be labeled.
Mariones Moliko
Native Freshfood
Minmatar Republic
#206 - 2016-11-07 14:44:57 UTC
When we get an update (new features or rewards) for PD?
Scatch Domination
Imperial Shipment
Amarr Empire
#207 - 2016-11-21 13:51:02 UTC  |  Edited by: Scatch Domination
I'm really afraid of my choices, at least for the cell variations.

http://i.imgur.com/p6v3wB2.png
zoomed:
http://i.imgur.com/8vn1EHY.png

So bridges can only happen in the red channel, "never ever" in the green?

Edit: I was also afraid of hitting "Abnormal Sample" for a sample that had scanlines in the red channel (it wasn't too impacting so i decided to not report it).

Would also suggest it may make results more precise if you use metrics on the "Success Rate" of certain pattern types and match them against unclear community choices, so certain people that are good of certain patterns may shift the result.

Example: You take the Classification results and 100% community matches for a certain patterns and show that sample to players who match 80%++ of that pattern in the last 15-30 submissions.

Edit: Shouldn't it be Nucleoli for the Classification? Since it covers close to only black holes in the nucleus?
Blue Mask: http://i.imgur.com/7kjdfeW.png
Green+Blue: http://i.imgur.com/6zeYMmO.png
Matthias Ancaladron
Imperial Shipment
Amarr Empire
#208 - 2016-11-26 04:58:38 UTC
I started playing this game but i was curious how um do you find a sistsrs of eve loyalty store? Do i have to go all the way to thera? I was thinking about grinding out one or two of those combat suits. One to keep and one to sell,
Memphis Baas
#209 - 2016-11-29 19:05:00 UTC  |  Edited by: Memphis Baas
Simplest way is to open the Agent Finder app in-game and search for a Sisters of EVE (corporation) agent. You can then see where their stations are.

I know a popular location is Arnon, where the Sisters of EVE Epic Arc starts, they have a station there. Gicodel, also, they have some agents there.

All you need is to find an SoE station, so you can click the LP Store button inside it. They have them in a bunch of places in high-sec, low-sec, and null.

EDIT: Also, the combat suits cannot be sold on the market, but they are available in the Contracts system for about 60 million ISK apiece, not bad. There's just a bug in their name that doesn't let you actually search the contracts interface for them; you have to set your Contract interface to show you Apparel, Outer Apparel, and then scroll down until you see the suits, male or female.

60 million ISK, as of yesterday. LP cost = 75,000 Project Discovery AK points + 37.5 million ISK. If you're starting Project Discovery from level 0, it'll take a while to get the AK points, as they are only rewarded as you level up, and only a few at a time.
Matthias Ancaladron
Imperial Shipment
Amarr Empire
#210 - 2016-11-30 23:20:17 UTC
Memphis Baas wrote:
Simplest way is to open the Agent Finder app in-game and search for a Sisters of EVE (corporation) agent. You can then see where their stations are.

I know a popular location is Arnon, where the Sisters of EVE Epic Arc starts, they have a station there. Gicodel, also, they have some agents there.

All you need is to find an SoE station, so you can click the LP Store button inside it. They have them in a bunch of places in high-sec, low-sec, and null.

EDIT: Also, the combat suits cannot be sold on the market, but they are available in the Contracts system for about 60 million ISK apiece, not bad. There's just a bug in their name that doesn't let you actually search the contracts interface for them; you have to set your Contract interface to show you Apparel, Outer Apparel, and then scroll down until you see the suits, male or female.

60 million ISK, as of yesterday. LP cost = 75,000 Project Discovery AK points + 37.5 million ISK. If you're starting Project Discovery from level 0, it'll take a while to get the AK points, as they are only rewarded as you level up, and only a few at a time.

Yeah i thought they were more than that. Ill just keep it. i was looking around and i thought they were worth alot more.
Ill just use the geno suit till i can get one for myself. And maybe a wirepoise facial implant. I think i like thst one the most from the previews ive seen on actual characters and not the silver heads. But i guess i could always trade it for another one if someone wants the one i have and i want a different one.

Ill look that up. I was looking up stations manually online and think the closest one I ound is 10-20 jumps away from where ive been hanging around. Dont remember how far off the top of my head. But im still a good ways off. I only have 15k ak at the momebt, i usually do them while im warping.
Memphis Baas
#211 - 2016-12-01 14:38:31 UTC  |  Edited by: Memphis Baas
Yeah there were lots of people who were really interested in helping out Project Discovery, much like everyone is into helping out Alphas right now. So they reached level 100+ and the AK rewards ramp up as you get higher level and higher accuracy. I got to about level 80 and that was 280,000 AK, almost 4 suits. So there's plenty of suits available, and anyone interested in the project can get the AK for more.

They also have that red-black "lab coat" outer, but like all outers of the same shape, it SUCKS because the character customization interface doesn't treat mini-dress + nylons/hosiery combinations as a sufficient replacement for pants. The lab coat is long enough for modesty, but the interface doesn't allow it.

I think that the white and red highlights on the SoE armor look better than the black tones of the Genolution suit, for women, especially given my (and the bleached white/blonde) hair colors that are accentuated by women's longer hair options.
Rekalia
Star Frontiers
Test Alliance Please Ignore
#212 - 2016-12-12 00:41:39 UTC
http://imgur.com/a/HP6dd

This one was pretty hard.

The one that is telling me is correct states about how it is at the edge of the blue areas.

However, these were in the center connected by a lot of red stringy bits. Was a little disappointed. But I'll keep it in mind if I come across it again.
Reaver Glitterstim
The Scope
Gallente Federation
#213 - 2016-12-26 07:41:57 UTC
I see a whole lot of samples with both cytoplasm and nucleoplasm, so it looks almost like there's a really even cytoplasm extending through the whole cell, even in the blue area.

I also was noticing the actual golgi apparatuses look nothing like the example, that's when I finally realized you can mouse over the example to see three alternative examples.

FT Diomedes: "Reaver, sometimes I wonder what you are thinking when you sit down to post."

Frostys Virpio: "We have to give it to him that he does put more effort than the vast majority in his idea but damn does it sometime come out of nowhere."

Zack Zamricon
Center for Advanced Studies
Gallente Federation
#214 - 2017-01-12 17:05:33 UTC
Pretty much all the samples are extremely difficult, mostly due to poor labeling of a lot of small buttons with inadequate examples to distinguish one from the other.

A redesign of the interface is reccomended.
Mariones Moliko
Native Freshfood
Minmatar Republic
#215 - 2017-01-13 18:58:29 UTC
When we get an Update for PD?
Nana Skalski
Taisaanat Kotei
#216 - 2017-01-28 16:14:04 UTC
Its a very good atlas of a cell, where you can see different parts of it if you point them with mouse. I hope it will help some people understand what is in the project discovery images.
Raz Ohr
Beyond SpaceTime
#217 - 2017-02-27 17:05:11 UTC
Hi,
it's not the first time but today I found what I think is an uncorrect classification and I want to post it to have feedbacks.


image

As highlighted there is also a cytokinetic bridge...
I think this one need to be fixed

Reaver Glitterstim
The Scope
Gallente Federation
#218 - 2017-02-28 08:05:41 UTC  |  Edited by: Reaver Glitterstim
Raz Ohr wrote:
Hi,
it's not the first time but today I found what I think is an uncorrect classification and I want to post it to have feedbacks.


image

As highlighted there is also a cytokinetic bridge...
I think this one need to be fixed


It's not definitely a cytokinetic bridge. It could just be a conglomeration of cytoplasm stains right in that spot. Note that it doesn't fan out at its ends.

I think it is a bridge, but it's an odd one alright.

FT Diomedes: "Reaver, sometimes I wonder what you are thinking when you sit down to post."

Frostys Virpio: "We have to give it to him that he does put more effort than the vast majority in his idea but damn does it sometime come out of nowhere."

Lukka
#219 - 2017-03-01 21:19:26 UTC
Raz Ohr wrote:
Hi,
it's not the first time but today I found what I think is an uncorrect classification and I want to post it to have feedbacks.


image

As highlighted there is also a cytokinetic bridge...
I think this one need to be fixed



There are a few for which classifications are incorrect. That is almost certainly marking a cytokinetic bridge, particularly as the tethered cytoplasm can be seen to be linking the cells at this spot.
Reaver Glitterstim
The Scope
Gallente Federation
#220 - 2017-03-09 02:38:22 UTC  |  Edited by: Reaver Glitterstim
Here's a weird one for you guys: http://imgur.com/gallery/MBQsz

It looks like some of the cells were dissolving when the image was taken. Three of them show very little cytoplasm red staining outside their nucleus, however their nucleus is in several small pieces in a clump, with heavy green staining throughout the fragments. The rest of the cells are largely unstained with green; however one of them has a very strong vesicle stain which makes it stand out from other cells, despite its blue+red stains making it appear to match the other cells.





Scatch Domination wrote:
So bridges can only happen in the red channel, "never ever" in the green?

Edit: I was also afraid of hitting "Abnormal Sample" for a sample that had scanlines in the red channel (it wasn't too impacting so i decided to not report it).

Generally everything you're looking for is in the green channel. The red and blue are there to help you see where the green specks are located within the cell. If the red or blue channel show something highly abnormal, you should mark abnormal sample. That's what I did with the above sample.

FT Diomedes: "Reaver, sometimes I wonder what you are thinking when you sit down to post."

Frostys Virpio: "We have to give it to him that he does put more effort than the vast majority in his idea but damn does it sometime come out of nowhere."