Wormholes

Are you going to be doing this solo or coming in with associates? Wormholes to/from class 1 systems are the only ones unable to support the transit of battleships, but you'll find the resources available in those systems to be somewhat less than desirable with respect to profits. You said you're not interested in Sleepers, though. What exactly are you looking to do in w-space?

You are better off just picking a hole you like with statics you like. Any wormhole will allow the passage of enough ships to take down your pos regardless of class or your pos configuration.

If your pos is your primary concern, you are doing it wrong.

POSes (and sleepers) aren't affected by WH system effects (aside from random bugs) so POSes in a Pulsar don't get additional shield HP.

I think your going to have to make a compromise somewhere:

C4s often give good seclusion but don't have the easiest of links to k-space, tho one with a C2 static won't be too bad but harder to find an empty one as they are fairly popular as C4s go.

C3s have good connections to k-space but you will get a lot of transit from higher class WH connections to deal with.

C3/4 have OK ladar/gravs but you will be missing out on the high end ones, but a C5/6 where the high end mining/gas sites are mostly found is not a good place to be if your intention is to invest in the system with a small corp.

C1 would be quite limiting but you'd probably be fairly much left alone and C2s are more useful if you are pro-actively running your w-space static for PVE or PVP.

C1s only connect to k-space and don't have very good resources available, but they would provide you with the least exposure to swarms of ships due to the very low transferable mass on their wormholes.

C2s will have slightly better resources, but their real benefit is that they have dual statics, so you get easy access to k-space and the ability to farm your static exit. If you don't plan on doing that then I'd suggest looking elsewhere.

C3s will give you good resources since you're going to be solo. They have higher mass limitations allowing for more ships, but in most cases a well-setup dickstar will cause wouldbe attackers to go elsewhere in search of easier targets.

C4s will never let you escape.

C5s are hellmode.

C6s... setting a large tower here solo would certainly draw attention, but there's a slight chance it would be viewed as an elaborate trap and be left alone. There's also a slight chance it would be stolen during the setup process and you'd be given a free ride on the hi-sec express.

I would personally advise a C2 with a high-sec simply because there are more of them (easier to get lost in the ranks) and a C1 highsec will only allow ships with masses under 20 million KG; therefore no orcas, no battleships; basically nothing above the mass of a battlecruiser.

Set your tower up like a Death Star or D*ck star and use a large tower (Amarr or Minmatar), and you shouldn't have any issues. If somebody tries to move in on you, hire somebody to kill them for you.

Svo.

Honestly this sound like a bad idea. The money makers in wspace are PI (more isk/hour than amount of isk) and sleepers. It used to be high end ores and gas were quite profitable. Current gas prices are pretty low with the advent of the Venture. The high end ores also have taken a huge dive in the wake of the drone poo nerf. Not to mention that a given system won't always have a ladar or grav site. I've seen weeks go by between grav. Mining is a nice thing to do a quiet day when you don't have more profitable things to do, but I'd argue you might as well setup in a .5 system in High Sec and mine there for the profit you'd make in wspace...

good luck with that.... considering WH anoms have no effect on any structures.

Blackholes work to a POS's advantage no matter fleet composition. Just have more than a few webs to slow those frigates down enough that your pos guns can actually hit them. Otherwise, a frigate can be used to run your pos out of ammo.

As to class of w-space system with a k-space connection. That's a big topic, many to chose from. Security? Well, higher class systems open up to lower class systems all the time. So you're likely to find someone opening to you who will pretty much lock down your system for the day.

Mining and manufacturing......both activities best done from k-space. Mining: lots of volume. You're going to need to run a refinery. In the best case a mobile refinery will cut your productivity by 25% and it can't be skilled away. So, do you take that hit? Or do you move out the ore to refine. You're going to want a HS static if you're moving lots of ore. You can also build a rorqual for compression but be aware than some groups moving through your system, if they see it, will burn you down just to ransom you for it.

Manufacturing, it's cheaper in k-space. What more is there to say?

How about gas reacting and/or ninjaing c5 mag/radar's for t3's components? Gas reacting and T3 reverse engineering can only be done in a POS. So, a c2 -> c5 & null might be what you're looking for. You'll have access to higher quality gases in the C5 for polymer reactions and access to gases from null for drug reactions. "But how do I get to hs?" you ask...well my friend, w-space has enough activity that you'll never go more than a few days without a route. If you're willing to roll your static c5 and/or null then it would not be hard to find a viable route anytime you choose.

It might be wise to do some day tripping so you can learn how w-space works. You would be surprised at the amount of traffic that sometimes occurs. There are corps whose only income is blapping folks in WHs. Especially solo folks.