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Inbreeding and Iceland

Author
2bhammered
Cyberpunk 2077
#21 - 2012-02-07 19:12:43 UTC
Jhagiti Tyran wrote:
2bhammered wrote:
Also I believe a medical doctor friend of mine told me once that sleeping with ones cousin and having kids is not the same as incest and perfectly ok, by scientific standards.


The doctor told you wrong, its OK in a certain sense but not entirely without consequence. Even 2nd or 3rd cousins having a child carries the same potential risk of inherited problems and birth defects of heavy drinking and smoking women in her 50s having a child.



I believe my doctor friend more than you, also to equate heavy drinking and smoking during pregnancy in her 50's to having a child with your third cousin is just, the dumbest thing I have heard today.
Jhagiti Tyran
Caldari Provisions
Caldari State
#22 - 2012-02-07 19:47:54 UTC  |  Edited by: Jhagiti Tyran
2bhammered wrote:
I believe my doctor friend more than you, also to equate heavy drinking and smoking during pregnancy in her 50's to having a child with your third cousin is just, the dumbest thing I have heard today.


Dont beleive me, see for yourself.

"41.2 percent of prereproductive deaths were associated with the expression of detrimental recessive genes, with equivalent values of 26.0, 14.9, and 8.1 percent for first cousins, first cousins once removed/double second cousins, and second cousins respectively."

http://www.jstor.org/pss/2137601

"A BBC report discussed Pakistanis in Britain, 55% of whom marry a first cousin.[190] Given the high rate of such marriages, many children come from repeat generations of first-cousin marriages. The report states that these children are 13 times more likely than the general population to produce children with genetic disorders, and one in ten children of first-cousin marriages in Birmingham either dies in infancy or develops a serious disability. The BBC also states that Pakistani-Britons, who account for some 3% of all births in the UK, produce "just under a third" of all British children with genetic illnesses. Published studies show that mean perinatal mortality in the Pakistani community of 15.7 per thousand significantly exceeds that in the indigenous population and all other ethnic groups in Britain. Congenital anomalies account for 41 percent of all British Pakistani infant deaths. The BBC story contained an interview with Myra Ali, whose parents and grandparents were all first cousins. She has a very rare recessive genetic condition, known as Epidermolysis bullosa which will cause her to lead a life of extreme physical suffering, limited human contact and probably an early death from skin cancer. Knowing that cousin marriages increase the probability of recessive genetic conditions, she is understandably against the practice. Finally, in 2010 the Telegraph reported that cousin marriage among the British Pakistani community resulted in 700 children being born every year with genetic disabilities."

http://www.telegraph.co.uk/health/healthnews/7957808/700-children-born-with-genetic-disabilities-due-to-cousin-marriages-every-year.html

"the average risk of birth defects in a child born of first cousins at 1.7–2.8% over an average base risk for non-cousin couples of 3%, or about the same as that of any woman over age 40. In terms of mortality, a 1994 study found a mean excess pre-reproductive mortality rate of 4.4%, While another study published in 2009 suggests the rate may be closer to 3.5%. Put differently, first-cousin marriage entails a similar increased risk of birth defects and mortality as a woman faces when she gives birth at age 41 rather than at 30."

"After repeated generations of cousin marriage the actual genetic relationship between two people is closer than the most immediate relationship would suggest. In Pakistan, where there has been cousin marriage for generations and the current rate may exceed 50%,"

http://www.consang.net/images/d/dd/01AHBWeb3.pdf

Thats just some of the research, the possible effects include miscarriage, post natal and infant death and a huge list of http://en.wikipedia.org/wiki/Polygenic_traits.

I think those pretty much count as consequences.

Rejoice in your education!
Herzog Wolfhammer
Sigma Special Tactics Group
#23 - 2012-02-07 21:42:37 UTC
What do you think the real reason is behind fanfest?


How many who go to fanfest are wondering why they pee funny for a week?

Bring back DEEEEP Space!

2bhammered
Cyberpunk 2077
#24 - 2012-02-07 23:51:25 UTC  |  Edited by: 2bhammered
Jhagiti Tyran wrote:
2bhammered wrote:
I believe my doctor friend more than you, also to equate heavy drinking and smoking during pregnancy in her 50's to having a child with your third cousin is just, the dumbest thing I have heard today.


Dont beleive me, see for yourself.

"41.2 percent of prereproductive deaths were associated with the expression of detrimental recessive genes, with equivalent values of 26.0, 14.9, and 8.1 percent for first cousins, first cousins once removed/double second cousins, and second cousins respectively."

http://www.jstor.org/pss/2137601

"A BBC report discussed Pakistanis in Britain, 55% of whom marry a first cousin.[190] Given the high rate of such marriages, many children come from repeat generations of first-cousin marriages. The report states that these children are 13 times more likely than the general population to produce children with genetic disorders, and one in ten children of first-cousin marriages in Birmingham either dies in infancy or develops a serious disability. The BBC also states that Pakistani-Britons, who account for some 3% of all births in the UK, produce "just under a third" of all British children with genetic illnesses. Published studies show that mean perinatal mortality in the Pakistani community of 15.7 per thousand significantly exceeds that in the indigenous population and all other ethnic groups in Britain. Congenital anomalies account for 41 percent of all British Pakistani infant deaths. The BBC story contained an interview with Myra Ali, whose parents and grandparents were all first cousins. She has a very rare recessive genetic condition, known as Epidermolysis bullosa which will cause her to lead a life of extreme physical suffering, limited human contact and probably an early death from skin cancer. Knowing that cousin marriages increase the probability of recessive genetic conditions, she is understandably against the practice. Finally, in 2010 the Telegraph reported that cousin marriage among the British Pakistani community resulted in 700 children being born every year with genetic disabilities."

http://www.telegraph.co.uk/health/healthnews/7957808/700-children-born-with-genetic-disabilities-due-to-cousin-marriages-every-year.html

"the average risk of birth defects in a child born of first cousins at 1.7–2.8% over an average base risk for non-cousin couples of 3%, or about the same as that of any woman over age 40. In terms of mortality, a 1994 study found a mean excess pre-reproductive mortality rate of 4.4%, While another study published in 2009 suggests the rate may be closer to 3.5%. Put differently, first-cousin marriage entails a similar increased risk of birth defects and mortality as a woman faces when she gives birth at age 41 rather than at 30."

"After repeated generations of cousin marriage the actual genetic relationship between two people is closer than the most immediate relationship would suggest. In Pakistan, where there has been cousin marriage for generations and the current rate may exceed 50%,"

http://www.consang.net/images/d/dd/01AHBWeb3.pdf

Thats just some of the research, the possible effects include miscarriage, post natal and infant death and a huge list of http://en.wikipedia.org/wiki/Polygenic_traits.

I think those pretty much count as consequences.

Rejoice in your education!



Rejoice in my education? Lol Ok where to begin, it is late so I will be brief, a your first source is something from somewhere back in 1994? Journal of science published peer review research I believe one suggesting that inbreeding on Iceland increased fertility, want a link? google it or use wiki page for inbreeding, yes there seems to be oneShocked second you proved my point yourself because if you took a few seconds to read what I wrote in that post you quote me on you'd see why I even went as far as calling someone "dumb".

Also from what I read according to latest data increased mortality is 3.5% by first cousin, wowzor, some say 4.4%, holy motha, and you even linked that to me with your postBig smile

That would equate to similar risk of someone having a childat the age of 41, whatever, and I believe smoking and alchohol abuse have a worse % of risk factor to pregnancy and birth defects. But don't quote me on that?!Twisted

But I agree there are risks, I do not agree that they are really worth taking note of especially when it comes to second or third cousin. Also, obviously it can't be that bad, we are discussing this on CCP forums, an Icelandic company and you are arguing with a Levi Lol...
Jhagiti Tyran
Caldari Provisions
Caldari State
#25 - 2012-02-08 00:34:42 UTC
2bhammered wrote:
Jhagiti Tyran wrote:
2bhammered wrote:
I believe my doctor friend more than you, also to equate heavy drinking and smoking during pregnancy in her 50's to having a child with your third cousin is just, the dumbest thing I have heard today.


Dont beleive me, see for yourself.

"41.2 percent of prereproductive deaths were associated with the expression of detrimental recessive genes, with equivalent values of 26.0, 14.9, and 8.1 percent for first cousins, first cousins once removed/double second cousins, and second cousins respectively."

http://www.jstor.org/pss/2137601

"A BBC report discussed Pakistanis in Britain, 55% of whom marry a first cousin.[190] Given the high rate of such marriages, many children come from repeat generations of first-cousin marriages. The report states that these children are 13 times more likely than the general population to produce children with genetic disorders, and one in ten children of first-cousin marriages in Birmingham either dies in infancy or develops a serious disability. The BBC also states that Pakistani-Britons, who account for some 3% of all births in the UK, produce "just under a third" of all British children with genetic illnesses. Published studies show that mean perinatal mortality in the Pakistani community of 15.7 per thousand significantly exceeds that in the indigenous population and all other ethnic groups in Britain. Congenital anomalies account for 41 percent of all British Pakistani infant deaths. The BBC story contained an interview with Myra Ali, whose parents and grandparents were all first cousins. She has a very rare recessive genetic condition, known as Epidermolysis bullosa which will cause her to lead a life of extreme physical suffering, limited human contact and probably an early death from skin cancer. Knowing that cousin marriages increase the probability of recessive genetic conditions, she is understandably against the practice. Finally, in 2010 the Telegraph reported that cousin marriage among the British Pakistani community resulted in 700 children being born every year with genetic disabilities."

http://www.telegraph.co.uk/health/healthnews/7957808/700-children-born-with-genetic-disabilities-due-to-cousin-marriages-every-year.html

"the average risk of birth defects in a child born of first cousins at 1.7–2.8% over an average base risk for non-cousin couples of 3%, or about the same as that of any woman over age 40. In terms of mortality, a 1994 study found a mean excess pre-reproductive mortality rate of 4.4%, While another study published in 2009 suggests the rate may be closer to 3.5%. Put differently, first-cousin marriage entails a similar increased risk of birth defects and mortality as a woman faces when she gives birth at age 41 rather than at 30."

"After repeated generations of cousin marriage the actual genetic relationship between two people is closer than the most immediate relationship would suggest. In Pakistan, where there has been cousin marriage for generations and the current rate may exceed 50%,"

http://www.consang.net/images/d/dd/01AHBWeb3.pdf

Thats just some of the research, the possible effects include miscarriage, post natal and infant death and a huge list of http://en.wikipedia.org/wiki/Polygenic_traits.

I think those pretty much count as consequences.

Rejoice in your education!



Rejoice in my education? Lol Ok where to begin, it is late so I will be brief, a your first source is something from somewhere back in 1994? Journal of science published peer review research I believe one suggesting that inbreeding on Iceland increased fertility, want a link? google it or use wiki page for inbreeding, yes there seems to be oneShocked second you proved my point yourself because if you took a few seconds to read what I wrote in that post you quote me on you'd see why I even went as far as calling someone "dumb".

Also from what I read according to latest data increased mortality is 3.5% by first cousin, wowzor, some say 4.4%, holy motha, and you even linked that to me with your postBig smile

That would equate to similar risk of someone having a childat the age of 41, whatever, and I believe smoking and alchohol abuse have a worse % of risk factor to pregnancy and birth defects. But don't quote me on that?!Twisted

But I agree there are risks, I do not agree that they are really worth taking note of especially when it comes to second or third cousin. Also, obviously it can't be that bad, we are discussing this on CCP forums, an Icelandic company and you are arguing with a Levi Lol...


Do you even know what's going on here? Let me break down in nice and easy to read and step by step.

1. You post anecdote about how medical doctor said it was perfectly "OK" to for cousins to have children

2. I post rebuttal and post an anecdote about the risks and consequence

3. You post rebuttal and call me dumb

4. I list links to research that points out lower risks for cousins having children roughly equivalent to an over 40s women having a child. There where further sources suggesting that after a generation or two the risks sky rocket far beyond that with consequences actually far worse than my smoking and drinking older mother with a greater risk of inheritable disorders, miscarriage, post natal and infant death

All i wanted to point out that its not medically "OK" it carries risks yet you had to be insulting.
2bhammered
Cyberpunk 2077
#26 - 2012-02-08 01:12:55 UTC  |  Edited by: 2bhammered
Jhagiti Tyran wrote:
2bhammered wrote:
Jhagiti Tyran wrote:
[quote=2bhammered]I believe my doctor friend more than you, also to equate heavy drinking and smoking during pregnancy in her 50's to having a child with your third cousin is just, the dumbest thing I have heard today.


Dont beleive me, see for yourself.

"41.2 percent of prereproductive deaths were associated with the expression of detrimental recessive genes, with equivalent values of 26.0, 14.9, and 8.1 percent for first cousins, first cousins once removed/double second cousins, and second cousins respectively."

http://www.jstor.org/pss/2137601

"A BBC report discussed Pakistanis in Britain, 55% of whom marry a first cousin.[190] Given the high rate of such marriages, many children come from repeat generations of first-cousin marriages. The report states that these children are 13 times more likely than the general population to produce children with genetic disorders, and one in ten children of first-cousin marriages in Birmingham either dies in infancy or develops a serious disability. The BBC also states that Pakistani-Britons, who account for some 3% of all births in the UK, produce "just under a third" of all British children with genetic illnesses. Published studies show that mean perinatal mortality in the Pakistani community of 15.7 per thousand significantly exceeds that in the indigenous population and all other ethnic groups in Britain. Congenital anomalies account for 41 percent of all British Pakistani infant deaths. The BBC story contained an interview with Myra Ali, whose parents and grandparents were all first cousins. She has a very rare recessive genetic condition, known as Epidermolysis bullosa which will cause her to lead a life of extreme physical suffering, limited human contact and probably an early death from skin cancer. Knowing that cousin marriages increase the probability of recessive genetic conditions, she is understandably against the practice. Finally, in 2010 the Telegraph reported that cousin marriage among the British Pakistani community resulted in 700 children being born every year with genetic disabilities."

http://www.telegraph.co.uk/health/healthnews/7957808/700-children-born-with-genetic-disabilities-due-to-cousin-marriages-every-year.html


http://www.consang.net/images/d/dd/01AHBWeb3.pdf

Thats just some of the research, the possible effects include miscarriage, post natal and infant death and a huge list of http://en.wikipedia.org/wiki/Polygenic_traits.

I think those pretty much count as consequences.

Rejoice in your education!




Do you even know what's going on here? Let me break down in nice and easy to read and step by step.

1. You post anecdote about how medical doctor said it was perfectly "OK" to for cousins to have children

2. I post rebuttal and post an anecdote about the risks and consequence

3. You post rebuttal and call me dumb

4. I list links to research that points out lower risks for cousins having children roughly equivalent to an over 40s women having a child. There where further sources suggesting that after a generation or two the risks sky rocket far beyond that with consequences actually far worse than my smoking and drinking older mother with a greater risk of inheritable disorders, miscarriage, post natal and infant death

All i wanted to point out that its not medically "OK" it carries risks yet you had to be insulting.


"The doctor told you wrong, its OK in a certain sense but not entirely without consequence. Even 2nd or 3rd cousins having a child carries the same potential risk of inherited problems and birth defects of heavy drinking and smoking women in her 50s having a child."

First you started by hyperbole so blame yourself, perhaps I should have been nicer and for that I apologise. But you saying "rejoice in your education" is baiting for the record. But I don't mind it Cool

Second, I just spoke with my doctor friend over the phone again and he said there could be risks but as of now there is no conclusive data on it, telling me that most studies fall within the margin of error and some studies, one I mentioned earlier pointed to the opposite. He said if asked by a patient he would reply that it is ok but if they want to be sure they should get a genetic test but because of the reason that he reccomends everyone to get tested as such diseases and complications can arise even if you have a child with someone of another race and again, no study that he knows of proves without a doubt that having a child with ones cousin has yielded more complications than those that do not. Iceland is a prime example.

Third, he also told me that, which I already knew, heavy smoking and abusive drinking and being pregnant above the age of 40 each by itself had a higher risk than having a child with ones cousin and that such data is well documented and no one argues the increased risks for old age to be pregnant, drinking or smoking. He said he'd rather have you marry your cousin then do either of those things if you worry about the risks of having a child.

Again, you are free to google this, research it or even speak to an MD yourself, I take his word for it but you never know rightStraight so feel free to prove me wrong. At the moment though, I tend to feel quite safe with believing him and what I have read myself etc. But then again, I would never **** my cousin in the first place, it would be to akward at family reuinions Lol
rodyas
Tie Fighters Inc
#27 - 2012-02-12 08:31:50 UTC
Man this thread made me feel inbreed.

Signature removed for inappropriate language - CCP Eterne

Nemesis Factor
Deep Core Mining Inc.
Caldari State
#28 - 2012-02-13 06:54:40 UTC
A little surprised this turned into a debate over the pros and cons of inbreeding.
Brisco County
Deep Core Mining Inc.
Caldari State
#29 - 2012-02-13 17:13:22 UTC
Herzog Wolfhammer wrote:
What do you think the real reason is behind fanfest?


How many who go to fanfest are wondering why they pee funny for a week?



They're harvesting our nerd genes to create a superior race of fat neckbearded pale skinned mutants.
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