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On the subject of bio-weapons

Author
Doctor Valate
Delve Medical Services
#1 - 2015-04-25 11:28:17 UTC
Greetings, IGS users.

As a medical researcher, I am occasionally irritated by persons coming into my office, and asking if I can design a bio-weapon for them. Most of them are capsuleers, with some ludicrous overblown megalomaniacal scheme to do heinous things to other people, for reasons that I do not care to know. But that's not unusual when dealing with capsuleers.

Instead, I wish to communicate my thoughts upon the subject of bio-weapons. Particularly synthetic bacteria, although the same points apply to viruses and other such.

Put simply, They are unrighteous, and anyone considering using them is a fool of the highest order.


Firstly, designing a bacterium, is an exercise in duplication. There are tens of thousands of worlds, with tens of thousands of species, already in existence, which produce substances capable of use as a bio-weapon, without all the rigmarole of designing one from scratch. Amnesiac shellfish poisoning as an example. Why attempt to create a bacterium from scratch, when there exists thousands of other bacteria that would fulfil that role just as well?

Secondly, a designed bacterium is relatively easy to reverse-engineer. All the genes used in its construction do something relevant to its function, and can be identified through simple processes. There aren't any extraneous genes that the bacterium picked up from the environment by chance. Every part of a designed bacterium does something, which makes counter-measures easy to design.

Thirdly, mutations in a designed bacterium make that bacterium dangerous to use as a weapon. A random mutation causing a change in function, mean that the intended effect may no longer work at all. Or alternatively, that the antidote no longer works on that bacterium, meaning that the weapon has gone out of control.

Fourthly, while it is possible to design a constructed bacterium that minimises or eliminates the two previously mentioned problems, such a bacterium would be an overblown monstrosity, ludicrously overengineered and ruinously expensive. Especially compared to the costs of isolating naturally occurring bacteria.

Thus, a designed bacterium is, redundant, inefficient, unstable, uncontrollable, and expensive.

A designed bio-weapon is a fools errand.


As for the application of bio weapons, there is only one, which is retribution against civilian populations. And given the difficulties of delivering a bio weapon to a planet, then it is far more effective and cheaper, to use such things as explosives, or other conventional weapons to achieve the same effect.

I do hear one suggested use for bio weapons. "But Doctor, it is so that the facility could be taken intact", says the person who wants a bio-weapon. Ludicrous. The same end can be achieved by other means. Especially if it is a science facility.

You see, most scientists are passionate about their work, and do not care much for politics. Instead of a ludicrous harebrained scheme to deploy bio-weapons against a science facility, swoop in and steal all the research data, it is far more effective to do things like this: Ask the scientist about the research.

"That's fascinating, Professor. But how did you solve the problem of X?" you ask the professor, and, being a Person of Science, the professor would be all too keen to expound upon their brilliance at solving problem X.


So, the design and use of bio-weapons is foolish and inefficient, and anyone considering it should be ashamed. Ashamed, I say!

Doctor Valerie Valate. Not to be confused with the other Valerie Valate.

Liam Antolliere
Doomheim
#2 - 2015-04-25 12:07:16 UTC
Doctor Valate wrote:
So, the design and use of bio-weapons is foolish and inefficient, and anyone considering it should be ashamed. Ashamed, I say!


I agree. Albeit for entirely different reasoning...

"Though the people may hate me, that does not relieve me of my charge."

Arkady Vachon
The Gold Angels
Sixth Empire
#3 - 2015-04-25 12:41:31 UTC
Doctor Valate wrote:


So, the design and use of bio-weapons is foolish and inefficient, and anyone considering it should be ashamed. Ashamed, I say!


Agree with this for a lot of reasons, some of them quite personal.

Nothing Personal - Just Business...

Chaos Creates Content

Gilan Isana
Science and Trade Institute
Caldari State
#4 - 2015-04-25 13:30:47 UTC
The day capsulers have to resort to bio-weapons is the beginning of our own destruction.

Was the Jovian disease an act of nature or was it created in a lab somewhere - either by accident or design. These seemingly immortal race suddenly had to face their own mortality and many died, before shutting themselves off from the rest of us.

Who is to say the same would not backfire and affect capsulers. A bio-weapon that was transfered to each clone on download would spell the end for us all.

The latest rumor I have heard for the drifters is that they are a faction of Jove that were infected with the disease, but not killed by it - cast out so they did not infect the rest of the Jovians, yet driven truly mad by the disease and now hell bent on exacting revenge for their eons spent in the wilderness.

Imagine the destruction that would be inflicted on the rest of us if some bio-weapon got out of control and turned a pirate faction or sub-group of capsulers equally mad, and hell bent on the destruction of all living things!!

Diana Kim
State Protectorate
Caldari State
#5 - 2015-04-25 14:58:02 UTC
Doctor Valate wrote:

Thus, a designed bacterium is, redundant, inefficient, unstable, uncontrollable, and expensive.

A designed bio-weapon is a fools errand.

Indeed, it sounds as is.
However, there is one possibility that only bio-weapon can achieve. And this is selectivity.

Different groups of organisms have different genome. It is easy to show, that it is simple to find a certain gene coding a certain protein in a given group of organisms, that is unique to them. It means you could possible develop an agent that would attack only species with given DNA fragment.

Usage of such agent could be incredible efficient. Lets imagine, that you have a planet X, inhabited by smart, progressive species A, and that it was bombed and occupied by lazy hedonistic parasitic species B, who halted prosperity of species A. In order to restore glory of species A you have to remove species B from the planet without damaging species A.

But if you apply traditional weapons to parasites B, you will damage good species A, as a collateral damage. If it would be possible to create bio-weapon that could affect only parasites B without infecting species A this will be way more efficient an humane, as species A won't be affected by this. And parasites B will be sufficiently removed, because they won't be able to hide, or to fool weapon by changing their color, size, shape, or to change their documents, or mimic biologically by other ways to species A, they won't be able to lie to a bio-weapon, as it will be targeting their proteins that only their DNA codes.

What do you think, doctor?

Honored are the dead, for their legacy guides us.

In memory of Tibus Heth, Caldari State Executor YC110-115, Hero and Patriot.

Gilan Isana
Science and Trade Institute
Caldari State
#6 - 2015-04-25 15:05:32 UTC
Diana Kim wrote:
Doctor Valate wrote:

Thus, a designed bacterium is, redundant, inefficient, unstable, uncontrollable, and expensive.

A designed bio-weapon is a fools errand.

Indeed, it sounds as is.
However, there is one possibility that only bio-weapon can achieve. And this is selectivity.

Different groups of organisms have different genome. It is easy to show, that it is simple to find a certain gene coding a certain protein in a given group of organisms, that is unique to them. It means you could possible develop an agent that would attack only species with given DNA fragment.

Usage of such agent could be incredible efficient. Lets imagine, that you have a planet X, inhabited by smart, progressive species A, and that it was bombed and occupied by lazy hedonistic parasitic species B, who halted prosperity of species A. In order to restore glory of species A you have to remove species B from the planet without damaging species A.

But if you apply traditional weapons to parasites B, you will damage good species A, as a collateral damage. If it would be possible to create bio-weapon that could affect only parasites B without infecting species A this will be way more efficient an humane, as species A won't be affected by this. And parasites B will be sufficiently removed, because they won't be able to hide, or to fool weapon by changing their color, size, shape, or to change their documents, or mimic biologically by other ways to species A, they won't be able to lie to a bio-weapon, as it will be targeting their proteins that only their DNA codes.

What do you think, doctor?


Kim,

Would species A be the caldari left on caldari prime, and species B their Gallente counterparts by any chance??

Shocked

Diana Kim
State Protectorate
Caldari State
#7 - 2015-04-25 15:08:52 UTC
Gilan Isana wrote:

Kim,

Would species A be the caldari left on caldari prime, and species B their Gallente counterparts by any chance??

Shocked


That's pure hypothetical reasoning.

Honored are the dead, for their legacy guides us.

In memory of Tibus Heth, Caldari State Executor YC110-115, Hero and Patriot.

Markus Error
Manfios
#8 - 2015-04-25 17:51:20 UTC
Mutation means bioweapons are entirely unpredictable.

Really, a soldier with a rifle can be far more selective about his targets.

"If it cannot be shot the #### down, it can always be blown the #### up."

-Unknown

Mizhir
Devara Biotech
#9 - 2015-04-25 18:14:13 UTC
As Markus Error pointed out bioweapons are extremely unpredictable. The problem with bioweapons is not a too low efficiency, but a too high efficiency.

❤️️💛💚💙💜

Lyn Farel
Societas Imperialis Sceptri Coronaeque
Khimi Harar
#10 - 2015-04-25 19:12:57 UTC
The only one that comes immediately to mind is Vitoc, that is unique enough in the fact that it never really derailed from the criteria it was designed upon, and continues to mutate according to the mutation patterns initially calculated.
Makoto Priano
Kirkinen-Arataka Transhuman Zenith Consulting Ltd.
Arataka Research Consortium
#11 - 2015-04-25 20:08:27 UTC
Ah, yes. Remember that time when the Blood Raiders used Insorum as a chemical weapon?

While I've had a Sabik doctor on my staff once before, and generally respect the medical capabilities of the Sani Sabik, there's a line between 'capable personnel' and 'someone to throw out an airlock and destroy the medclones of,' which is crossed the moment that person becomes a Blood Raider.

Given her history, I'd assume Valate is one of the latter.

Itsukame-Zainou Hyperspatial Inquiries: exploring the edge of the known, advancing the state of the art. Would you like to know more?

Gilan Isana
Science and Trade Institute
Caldari State
#12 - 2015-04-25 23:43:15 UTC
Lyn Farel wrote:
The only one that comes immediately to mind is Vitoc, that is unique enough in the fact that it never really derailed from the criteria it was designed upon, and continues to mutate according to the mutation patterns initially calculated.


Is vitoc biological? my understanding was that it was a chemical agent requiring an antidote rather than a biological one.

Though I may have mis-understood and stand quite ready to be corrected and educated!
Lyn Farel
Societas Imperialis Sceptri Coronaeque
Khimi Harar
#13 - 2015-04-26 08:43:43 UTC
The vitoxin agent is a bioengineered virus that infects cells and makes them produce a toxin (vitoxin). Vitoxin is lethal, unless countered with a neutralizing chemical particle (Vitoc), or cured with Insorum.

The virus mutates regularly according to patterns that allow the imperial producing firms to release new versions of Vitoc every time it does.

Which makes it probably the only bioweapon that is sufficiently clean and flawless that I know of today.
Jurou Yuan
Wolfraam 74
#14 - 2015-04-26 09:34:54 UTC
Whatever gets a job done is alright by me.
Claudia Osyn
Non-Hostile Target
Wild Geese.
#15 - 2015-04-27 02:53:51 UTC  |  Edited by: Claudia Osyn
Diana Kim wrote:
Doctor Valate wrote:

Thus, a designed bacterium is, redundant, inefficient, unstable, uncontrollable, and expensive.

A designed bio-weapon is a fools errand.

Indeed, it sounds as is.
However, there is one possibility that only bio-weapon can achieve. And this is selectivity.

Different groups of organisms have different genome. It is easy to show, that it is simple to find a certain gene coding a certain protein in a given group of organisms, that is unique to them. It means you could possible develop an agent that would attack only species with given DNA fragment.

Usage of such agent could be incredible efficient. Lets imagine, that you have a planet X, inhabited by smart, progressive species A, and that it was bombed and occupied by lazy hedonistic parasitic species B, who halted prosperity of species A. In order to restore glory of species A you have to remove species B from the planet without damaging species A.

But if you apply traditional weapons to parasites B, you will damage good species A, as a collateral damage. If it would be possible to create bio-weapon that could affect only parasites B without infecting species A this will be way more efficient an humane, as species A won't be affected by this. And parasites B will be sufficiently removed, because they won't be able to hide, or to fool weapon by changing their color, size, shape, or to change their documents, or mimic biologically by other ways to species A, they won't be able to lie to a bio-weapon, as it will be targeting their proteins that only their DNA codes.

What do you think, doctor?

If species A was really that smart, species B wouldn't have gotten the best of them, huh? Therefore species B is the dominant being and the prime candidate for evolution..... Roll


Also, Bio-weapon are by no means humane. Nor are they as reliable as you make them out to be.

A little trust goes a long way. The less you use, the further you'll go.

Elmund Egivand
Tribal Liberation Force
Minmatar Republic
#16 - 2015-04-27 03:44:30 UTC  |  Edited by: Elmund Egivand
Unless the bioweapon agent uses DNA rather than RNA, comes with multiple kinds of HSPs (Heat Shock Proteins) to minimise chance of degradation or mutation of the genetic material and, maybe, capped with telomeres or comes with a sequence that encodes an enzyme that degrades the DNA or the transcription or translation factors (or the sequence that encodes for both).

But really, it's probably easier to just design a nanite to do the same thing. Even a heat and pH-resistant protein-based nanite (prion-analogue) is alot less unpredictable.

A Minmatar warship is like a rusting Beetle with 500 horsepower Cardillac engines in the rear, armour plating bolted to chassis and a M2 Browning stuck on top.

Lunarisse Aspenstar
Societas Imperialis Sceptri Coronaeque
Khimi Harar
#17 - 2015-04-30 17:03:00 UTC
Liam Antolliere wrote:
Doctor Valate wrote:
So, the design and use of bio-weapons is foolish and inefficient, and anyone considering it should be ashamed. Ashamed, I say!


I agree. Albeit for entirely different reasoning...


Likewise.