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Project Discovery: Challenging & Interesting Samples

First post
Author
Azuriel
Saints of the Sword
#121 - 2016-03-25 00:40:14 UTC
Project Discovery,

Please confirm that I was wrong on this classification. I put cytoskeleton (cytokinetic bridge) because to the top right of the bottom-most cell I clearly see one. Let me know if my eyes are playing tricks.

http://uploadpie.com/HmEUW


Thanks
Memphis Baas
#122 - 2016-03-25 01:23:26 UTC
IMO although the kinetic bridge shape is there (in red), it's not lit up in green, so I wouldn't have chosen it as an answer.

What they're doing is they're coloring in green one protein at a time, and then we're supposed to identify where in the cell the green protein is hiding. So a cell can have a nucleus, cytoplasm, and a kinetic bridge, but if none of those are green (or with dots), then the protein that that sample is about is not there.

Krevnos
Back Door Burglars
#123 - 2016-03-25 01:25:44 UTC
Here's an interesting one I came across. It looks as though the stain might be binding cilia:

http://imgur.com/1naVxSY
Memphis Baas
#124 - 2016-03-25 01:28:35 UTC  |  Edited by: Memphis Baas
Nuclear many dots, cytoplasm, and plasma membrane.

Incidentally, that website is viewable through the in-game browser, so we can look at extra examples. Just create a bookmark in the in-game browser. EDIT: you can also remove the red, green, blue on the website in each image, through the in-game browser too. So the examples are actually better.
Vardec Crom
The Harpooner's Rest
#125 - 2016-03-25 04:08:01 UTC
Azuriel wrote:
Project Discovery,

Please confirm that I was wrong on this classification. I put cytoskeleton (cytokinetic bridge) because to the top right of the bottom-most cell I clearly see one. Let me know if my eyes are playing tricks.

http://uploadpie.com/HmEUW


Thanks


I agree that it's there but I don't think it's stained.
Schnuckelpuppe
Native Freshfood
Minmatar Republic
#126 - 2016-03-26 12:17:46 UTC
@Memphis Baas: Nice website :)

Still, sometimes i think i just get trolled: http://imgur.com/QIAQhxm
Demica Diaz
SE-1
#127 - 2016-03-26 12:39:36 UTC
Too good to be true. In EVE, it HAS to be a trap... Image
Krevnos
Back Door Burglars
#128 - 2016-03-26 14:40:06 UTC
Demica Diaz wrote:
Too good to be true. In EVE, it HAS to be a trap... Image


LOL spot the control slide!
Galaxxis
Unicorn Rampage
#129 - 2016-03-26 18:31:26 UTC
Demica Diaz wrote:
Too good to be true. In EVE, it HAS to be a trap... Image


It's clearly cytoplasm!! *repeatedly slams the cytoplasm button*
Cyndrogen
The Greatest Corp in the Universe
#130 - 2016-03-26 18:43:45 UTC
Great idea to post these, I'm also having a hard time nailing down some of the samples and I'm starting to realize why this was released as a mini game. I wish there was a way to do this in game, to share samples or somehow team up and work together. I'm new to the mini game and also to cell research, not my profession, but I am a visual artist and I am very good at spotting patterns and colors. So far I have a decent rate of correct guesses but I always get samples which surprise me and the correct answer is puzzling based on the description.

I guess we could just use teamspeak, form a fleet and post images online to try and reach a better consensus and also learn to better identify these. I know I could definitely use a mentor on this one.

Every day in every way I improve my skills and get better.

Cyndrogen
The Greatest Corp in the Universe
#131 - 2016-03-26 20:01:41 UTC
I was so sure I got this one right .... then this happened

closeup
http://imgur.com/ObbKHRs

same image zoomed out
http://imgur.com/ps9qG27


Every day in every way I improve my skills and get better.

Cyndrogen
The Greatest Corp in the Universe
#132 - 2016-03-26 20:21:10 UTC  |  Edited by: Cyndrogen
I just got a really weird sample.... at first glance it looks obvious but then it doesn't really fit into any category 100%

http://imgur.com/Wi6KjrS


more detail
http://imgur.com/BMsSyd1

Every day in every way I improve my skills and get better.

Rakin o'Dubois
Center for Advanced Studies
Gallente Federation
#133 - 2016-03-27 12:55:19 UTC
Schnuckelpuppe wrote:

Still, sometimes i think i just get trolled: http://imgur.com/QIAQhxm


I got the exact same image and totally agree with your classification. I did the same.

I wonder how much screwed the baseline is due to the community consensus approach. Is there anything known on how they avoid those effects?

Cheers
Rakin
Beta Maoye
#134 - 2016-03-27 15:57:43 UTC
This one missed green and blue parts. http://uploadpie.com/Voupw
Krevnos
Back Door Burglars
#135 - 2016-03-27 16:53:22 UTC
Beta Maoye wrote:
This one missed green and blue parts. http://uploadpie.com/Voupw


Yeah, Hoescht and FITC stains didn't bind. Report as abnormal sample.
Krevnos
Back Door Burglars
#136 - 2016-03-27 16:57:12 UTC  |  Edited by: Krevnos
Rakin o'Dubois wrote:
Schnuckelpuppe wrote:

Still, sometimes i think i just get trolled: http://imgur.com/QIAQhxm


I got the exact same image and totally agree with your classification. I did the same.

I wonder how much screwed the baseline is due to the community consensus approach. Is there anything known on how they avoid those effects?

Cheers
Rakin



They use data analysis and draw up graphs of the likelihood of 'incorrect result' from the community based on percentage consensus. Draw a graph and pick a 'cut-off' consensus for which they will accept as the community being correct. As with all science, some of the results will be wrong, but they will be able to minimise this as required. They can even estimate their error rate with reasonable precision.

Data can also be cleaned up by removing all data entries by repeat offenders of the 'cytoplasm, nucleus' trick. Additionally, they can opt to look at data from the 90%+ graded players where overall community consensus is middling. There are many ways they can improve their data set to obtain best results.
Beta Maoye
#137 - 2016-03-28 05:55:28 UTC
This one is so colourful. Cells are like small islands connected by man-made straight bridges. http://uploadpie.com/dPHno
HPA Illuminator
H P A
C C P Alliance
#138 - 2016-04-01 10:36:47 UTC
Rakin o'Dubois wrote:
Schnuckelpuppe wrote:

Still, sometimes i think i just get trolled: http://imgur.com/QIAQhxm


I got the exact same image and totally agree with your classification. I did the same.

I wonder how much screwed the baseline is due to the community consensus approach. Is there anything known on how they avoid those effects?

Cheers
Rakin


Sorry about that, it's a known error that we will correct asap.
HPA Illuminator
H P A
C C P Alliance
#139 - 2016-04-01 10:38:26 UTC
Krevnos wrote:
Here's an interesting one I came across. It looks as though the stain might be binding cilia:

http://imgur.com/1naVxSY


Lovely sample! We don't have ciliated cells (unfortunately), so what you see here are membrane protrusions (which is really unusual to find, most cell membrane stainings don't have them).
HPA Illuminator
H P A
C C P Alliance
#140 - 2016-04-01 10:39:56 UTC
Azuriel wrote:
Project Discovery,

Please confirm that I was wrong on this classification. I put cytoskeleton (cytokinetic bridge) because to the top right of the bottom-most cell I clearly see one. Let me know if my eyes are playing tricks.

http://uploadpie.com/HmEUW


Thanks


Memphis was spot on with the explanation! (also the image link expired, you might wanna consider using imgur or puush instead? I had a look at it a few days ago though)